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Nucleic Acid Organizations Visualized by Scanning Force Microscopy
Author(s) -
Bohley C.,
Matern D.,
Bischoff G.,
Meister W.V.,
Kargov S.,
Lindau S.,
Barthel J.,
Hoffmann S.
Publication year - 1997
Publication title -
surface and interface analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.52
H-Index - 90
eISSN - 1096-9918
pISSN - 0142-2421
DOI - 10.1002/(sici)1096-9918(199706)25:7/8<614::aid-sia287>3.0.co;2-r
Subject(s) - scanning force microscopy , atomic force microscopy , mesophase , substrate (aquarium) , nucleic acid , scanning probe microscopy , nanotechnology , microscopy , chemistry , graphite , materials science , crystallography , composite material , optics , physics , optoelectronics , liquid crystal , biology , biochemistry , ecology
Both DNA and RNA domains and microdomains—to a certain degree comparable to self‐organizational mesophase areas—have been visualized as graphite surface adlayers by scanning force microscopy in contact force mode. More polar substrate surfaces, sharper tip geometries and tapping mode procedures proved less favourable, due to sample distortions and prevention of organization within the adlayer by dominant adhesive forces in the interface.© 1997 John Wiley & Sons, Ltd.