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Positive chemical ionization and tandem mass spectrometric fragmentation for the gas chromatographic analysis of β ‐agonists using the ion trap technique
Author(s) -
Biancotto Giancarlo,
Angeletti Roberto,
Traldi Pietro,
Guidugli Federico
Publication year - 1999
Publication title -
journal of mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1076-5174
DOI - 10.1002/(sici)1096-9888(199912)34:12<1346::aid-jms893>3.0.co;2-#
Subject(s) - chemistry , fragmentation (computing) , ion trap , chromatography , tandem , chemical ionization , tandem mass spectrometry , ion , analytical chemistry (journal) , mass spectrometry , ionization , selected reaction monitoring , organic chemistry , aerospace engineering , computer science , operating system , engineering
A procedure is described for the determination of three characteristic β‐agonists (clenbuterol, terbutalin and salbutamol) based on the formation of the corresponding protonated molecules and related collisional experiments. Quantification was carried out on selected collisional fragments and the reproducibility of the relative abundances of these fragments was estimated. The performance of the method was tested on bovine urine samples spiked at the lowest level of 0.2 ng ml −1 in each of the chosen compounds. Copyright © 1999 John Wiley & Sons, Ltd.