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Is the kinetic method a thermodynamic method?
Author(s) -
Armentrout P. B.
Publication year - 1999
Publication title -
journal of mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1076-5174
DOI - 10.1002/(sici)1096-9888(199902)34:2<74::aid-jms794>3.0.co;2-6
Subject(s) - chemistry , kinetic energy , dissociation (chemistry) , thermodynamics , collision , theoretical physics , statistical physics , classical mechanics , computer science , physics , computer security
The kinetic method is examined from the point of view of a proponent of a complementary and sometimes competitive technique, threshold collision‐induced dissociation. Limitations in the kinetic method and assumptions that have not been thoroughly examined in the literature are pointed out. A case study involving recent experiments in the author's laboratory is used to illlustrate the importance of including entropic effects in the data analysis, even for systems where the ligands are fairly similar. The author concludes by encouraging the use of the advanced kinetic methods outlined by Cooks et al . in the accompanying Commentary. Copyright © 1999 by John Wiley & Sons, Ltd.