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Structural Analysis of Derivatized Oligosaccharides Using Post‐source Decay Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry
Author(s) -
Lemoine J.,
Chirat F.,
Domon B.
Publication year - 1996
Publication title -
journal of mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1076-5174
DOI - 10.1002/(sici)1096-9888(199608)31:8<908::aid-jms376>3.0.co;2-d
Subject(s) - chemistry , mass spectrometry , fragmentation (computing) , fast atom bombardment , field desorption , analytical chemistry (journal) , yield (engineering) , matrix assisted laser desorption/ionization , ionization , desorption , sample preparation in mass spectrometry , benzylamine , protein mass spectrometry , mass spectrum , chromatography , protonation , atmospheric pressure laser ionization , metastability , tandem mass spectrometry , electrospray ionization , photoionization , organic chemistry , adsorption , ion , materials science , computer science , metallurgy , operating system
Structural information on oligosaccharides was obtained by post‐source decay matrix‐assisted laser desorption/ionization mass spectrometry. A systematic study of derivatized oligosaccharides showed that products relatively aminated with benzylamine allow the formation of [M+H] + molecular species. Metastable protonated species decompose in the field‐free region (post‐source decay) to yield predictable and reproducible fragmentation patterns. Information on sugar sequence and branching can be derived from such mass spectra.