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Development and pathway formation of peripheral neurons during leech embryogenesis
Author(s) -
Huang Yueqiao,
Jellies John,
Johansen Kristen M.,
Johansen Jørgen
Publication year - 1998
Publication title -
journal of comparative neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.855
H-Index - 209
eISSN - 1096-9861
pISSN - 0021-9967
DOI - 10.1002/(sici)1096-9861(19980803)397:3<394::aid-cne6>3.0.co;2-y
Subject(s) - leech , biology , anatomy , peripheral , neuroscience , sensory system , embryogenesis , dorsum , neuron , embryo , microbiology and biotechnology , operating system , computer science , world wide web
By labeling the germinal plates of staged leech embryos with monoclonal antibodies to the immunoglobulin superfamily member Tractin, we have documented the distribution and initial development of peripheral neurons in a hirudinid leech. We find, in addition to sensillar and extrasensillar sensory neurons, that there are 21 identifiable peripheral neurons in each hemisegment. These neurons are found in highly stereotyped positions, and all but two of them are associated with the segmental nerves. We show that eight of the peripheral neurons have the characteristic morphology of stretch receptor neurons and that they form a circumferentially distributed grid aligned in such a way that each of five specialized longitudinal muscle fascicles are monitored by at least two stretch receptor cells covering ventral, lateral, and dorsal regions of the body wall. Furthermore, we show that, in contrast to the dorsal posterior nerve, which is pioneered by central projections, the pathways of the three remaining segmental nerves are likely to be pioneered or guided by peripheral neurons. J. Comp. Neurol. 397:394–402, 1998. © 1998 Wiley‐Liss, Inc.