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Dynamic T1‐weighted magnetic resonance imaging of interstitial laser photocoagulation in the liver: Observations on in vivo temperature sensitivity
Author(s) -
Fried Marvin P.,
Morrison Paul R.,
Hushek Stephen G.,
Kernahan Gilberto A.,
Jolesz Ferenc A.
Publication year - 1996
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/(sici)1096-9101(1996)18:4<410::aid-lsm11>3.0.co;2-7
Subject(s) - magnetic resonance imaging , nuclear magnetic resonance , in vivo , sensitivity (control systems) , laser , materials science , nuclear medicine , medicine , chemistry , radiology , optics , physics , biology , microbiology and biotechnology , electronic engineering , engineering
Background and Objective Magnetic resonance imaging's (MRI) potential to monitor interstitial laser photocoagulation (ILP) has been previously demonstrated and is further tested here with improved spatial and temporal resolution. Study Design/Materials and Methods In vivo experiments employed fiber‐delivered 1,064 nm light (3.0 W, 150 sec) in six rabbit livers monitored under T1‐weighted FSE MRI as 1 image/10 sec and a 3 mm thick 8 cm FOV. Image signal intensities (SI) were compared with temperatures (T) at 7, 10, and 15 mm from the fiber. Results Data showed 33°C < T < 60°C. SI did not vary inverse‐linearly with T; changes in the tissue altered the MRI signal interfering with the SI changes due to temperature. Conclusion MRI cannot map SI‐derived temperatures over the entire treatment site. The role of MRI's temperature sensitivity must be coordinated with organ‐ and dose‐specific tissue changes. © 1996 Wiley‐Liss, Inc.