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Attempt to obtain greater dermal depth of vascular injury using dye‐enhanced laser technique: A new approach
Author(s) -
Aihara Hideo,
Tanino Ryuzaburo,
Osada Mitsuhiro,
Yoshiyuki Osamura R.
Publication year - 1996
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/(sici)1096-9101(1996)18:3<260::aid-lsm7>3.0.co;2-q
Subject(s) - ruby laser , laser , prussian blue , dye laser , materials science , irradiation , absorbance , penetration (warfare) , penetration depth , optics , chemistry , electrode , physics , operations research , nuclear physics , electrochemistry , engineering
Background and Objective Although pulsed dye laser has been successfully used in the treatment of portwine stains, a number of patients had incomplete clearance because the depth of penetration by the pulsed dye laser was inadequate. This study was performed to establish the greater penetration depth of vascular injury using a dye‐enhanced laser technique. Study Design/Materials and Methods The ruby laser at 694.3 nm was used, and the corresponding specific dye was Prussian blue solution (maximum absorbance 694 nm). We compared the penetration depth of vascular injury by the ruby laser irradiation after the Prussian blue injection with that by the dye laser irradiation. A flashlamp dye laser with a pulse duration of 300 μsec and a 5 mm diameter spot size was used to 6.2 J/cm 2 at 590 nm. The Prussian blue solution was injected into the superficial epigastric artery of white male Japanese rabbits, immediately followed by the ruby laser exposure to 6.2 J/cm 2 at a pulse duration of 283 μsec in a 15 × 15mm spotsize. Depth of penetration was measured from the dermoepidermal junction to the deepest site of vascular injury at 24 hours after laser exposure. Results Mean penetration of 590 nm of the dye laser light was 1.45 mm; mean penetration of the 694.3 nm ruby laser irradiation after the Prussian blue injection was 2.33 mm. Ruby laser penetration was greater than that of the dye laser. Conclusion This study emphasizes that the ruby laser irradiation after the Prussian blue injection can induce deeper vascular injury than the dye laser inducing similar pathological changes. © 1996 Wiley‐Liss, Inc.