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Function and complications after ablative and limb‐salvage therapy in lower extremity sarcoma of bone
Author(s) -
Renard Auke J.,
Veth René P.,
Schreuder H.W. Bart,
van Loon Corné J.,
Koops Heimen Schraffordt,
van Horn Jim R.
Publication year - 2000
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/(sici)1096-9098(200004)73:4<198::aid-jso3>3.0.co;2-x
Subject(s) - medicine , ablative case , amputation , surgery , knee joint , sarcoma , arthrodesis , radiation therapy , alternative medicine , pathology
Background and Objectives The functional results and the complications after several limb‐saving and ablative treatments because of lower extremity bone sarcoma were evaluated. Methods Seventy‐seven surviving patients were evaluated according to the MSTS (American Musculoskeletal Tumor Society) functional rating system. Fifty‐two patients had limb‐saving and 25 had ablative therapy. Median follow‐up was 97 months in the limb‐saving group and 112 months in the ablative group. Results Functional results in the limb‐saving group were significantly better than in the ablative group ( P = 0.0001). Functional results in patients with tumors about the knee joint were significantly better ( P = 0.0064) after limb‐saving surgery (i.e., endoprosthesis, knee arthrodesis, or rotationplasty) compared to functional results after ablative surgery (i.e., hip or knee disarticulation or above‐the‐knee amputation). Complications were 3 times more common after limb‐salvage procedures and 4 times more common after endoprosthetic reconstructions compared to after ablative procedures. Complications after limb‐saving therapy were fewest in tumors about the knee joint. In 3/28 patients, the endoprosthetic reconstruction had to be converted to an amputation. Conclusions Functional results were significantly better after limb‐saving compared to after ablative therapy. Complications, however, were more common after limb‐saving therapy. J. Surg. Oncol. 2000;73:198–205 . © 2000 Wiley‐Liss, Inc.