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Early detection of hepatocellular carcinoma in hepatitis‐B‐positive renal transplant recipients
Author(s) -
Tang S.,
Lo C. M.,
Chan T. M.,
Lai K. N.
Publication year - 1999
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/(sici)1096-9098(199910)72:2<99::aid-jso11>3.0.co;2-1
Subject(s) - hepatocellular carcinoma , medicine , malignancy , hepatitis b virus , gastroenterology , pathogenesis , transplantation , hepatitis b , epidemiology , alpha fetoprotein , liver transplantation , oncology , virus , immunology
Hepatocellular carcinoma (HCC) is a leading cause of malignancy after renal transplantation in Asia, where hepatitis B virus infection is endemic. Early detection and resection are the key to successful treatment because the mortality rate for HCC is high. The value of α‐fetoprotein monitoring in the early detection of HCC in renal transplant recipients has not been reported before. We describe 2 patients who had successful resection of HCC following early diagnosis by α‐fetoprotein monitoring. The epidemiology of post‐transplant HCC in various parts of the world and its pathogenesis are discussed. J. Surg. Oncol. 1999;72:99–101. © 1999 Wiley‐Liss, Inc.