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Unexplained decrease in measured oxygen saturation by pulse oximetry following injection of Lymphazurin 1% (isosulfan blue) during a lymphatic mapping procedure
Author(s) -
Coleman Robert L.,
Whitten Charles W.,
O'Boyle John,
Sidhu Bobbie
Publication year - 1999
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/(sici)1096-9098(199902)70:2<126::aid-jso12>3.0.co;2-p
Subject(s) - pulse oximetry , medicine , oxygen saturation , pulse (music) , saturation (graph theory) , lymphatic system , anesthesia , concomitant , oxygen , surgery , optics , pathology , chemistry , physics , mathematics , organic chemistry , combinatorics , detector
A rare case of alteration in measured pulse oximetry during a lymphatic mapping procedure for cervical carcinoma is reported. Over a 5‐min period following injection of perilesional Lymphazurin 1% dye (3 ml total), a profound pulse oximetry desaturation was observed. Concomitant arterial blood gas determinations confirmed patient's well‐being. Interaction of this agent's absorptive spectroscopy and wavelengths used to measure oxygen saturation by commercial pulse oximetry devices is suspected. J. Surg. Oncol. 1999;70:126–129. © 1999 Wiley‐Liss, Inc.