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Contemporary brachytherapy approaches in non–small‐cell lung cancer
Author(s) -
Hilaris Basil S.,
Mastoras Dina A.
Publication year - 1998
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/(sici)1096-9098(199812)69:4<258::aid-jso11>3.0.co;2-a
Subject(s) - medicine , brachytherapy , lung cancer , radiology , external beam radiation , radiation therapy , chemotherapy , external beam radiotherapy , nuclear medicine , oncology , surgery
Brachytherapy has the ability to deliver a higher tumor dose compared to external beam irradiation, while sparing normal tissue outside the tumor; it is the most effective means of delivering conformal radiation and can be tailored to clinical circumstances, either at open surgery or in an ambulatory setting, which is currently the preferred method. Intraoperative lung and/or endobronchial brachytherapy in the management of non–small‐cell lung cancer offers a good curative potential in patients with accessible localized tumors, well defined and small to moderate in size, that have not metastasized to the lymph nodes and are technically or medically inoperable. Effective palliation can be frequently obtained by endobronchial brachytherapy on an outpatient procedure basis. Brachytherapy administered simultaneously with chemotherapy is better tolerated than a course of external beam irradiation and chemotherapy. J. Surg. Oncol. 1998;69:258–264. © 1998 Wiley‐Liss, Inc.