Premium
Extremity soft tissue sarcoma with metastases to abdominopelvic surfaces
Author(s) -
Zanarini Danilo,
Sugarbaker Paul H.
Publication year - 1997
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/(sici)1096-9098(199701)64:1<68::aid-jso13>3.0.co;2-s
Subject(s) - medicine , sarcoma , soft tissue , abdomen , soft tissue sarcoma , pelvis , metastasis , hemipelvectomy , chemotherapy , peritoneum , trabectedin , surgery , radiology , pathology , cancer
Background In a majority of patients with extremity soft tissue sarcoma, the lungs are the first site at which recurrent disease is detected. Other common sites of recurrence are the resection site, bone metastasis, and liver metastasis. Although abdomino‐pelvic sarcomatosis is common as a site of recurrence for visceral and retroperitoneal sarcoma, it has not been previously reported for extremity sarcoma. Method We present three patients in whom extremity soft tissue sarcoma metastasized to the peritoneal surfaces, and in all three patients this was symptomatically the dominant site for recurrence. All of them underwent a palliative surgical cytoreduction and were then treated with intraperitoneal chemotherapy. Results In two of the three patients, isolated progression of peritoneal sarcomatosis has again occurred; one patient remains disease free at 14 months. Conclusions Metastasis to peritoneal surfaces within the abdomen and pelvis must be considered a possible site for systemic dissemination of extremity soft tissue sarcomas. Effective treatments for sarcoma spread to peritoneal surfaces would benefit this small but symptomatic group of patients. J. Surg. Oncol. 64:68–73 © 1997 Wiley‐Liss, Inc.