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Interval carcinomas of the breast: A group with intermediate outcome
Author(s) -
Schroën Alma A.,
Wobbes Theo,
van der Sluis Rigtje F.
Publication year - 1996
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/(sici)1096-9098(199611)63:3<141::aid-jso2>3.0.co;2-d
Subject(s) - medicine , carcinoma , cancer , stage (stratigraphy) , breast carcinoma , retrospective cohort study , oncology , breast cancer , gastroenterology , paleontology , biology
Background Interval carcinoma is defined as a carcinoma detected between two mammographic screening rounds after a negative screening. By some authors these carcinomas are considered to be more aggressive than screen‐detected carcinomas. Methods In a group of 937 patients referred for breast cancer in the period 1975–1990, 76 interval carcinoma patients were treated. In a retrospective study the outcome was studied of patients with an interval carcinoma in comparison with patients with screen‐detected carcinomas and of patients with clinically detected carcinomas outside the screening program. Results No significant difference was found in the 5‐year and 10‐year disease‐free survival of patients with interval carcinoma (80%, 68%) and the screen‐detected group (89%, 81%) ( P = 0.12). The interval group did significantly better than the patients with carcinomas detected outside the screening program ( P = 0.03). Conclusion Interval‐detected cancers for patients in the screening program had an outcome intermediate between patients with screen‐detected cancers and patients with cancers detected outside the screening program. The difference between interval‐detected cancers and cancers detected outside the screening program was significant, whereas the difference between screen‐detected and interval cancers was not. © 1996 Wiley‐Liss, Inc.