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Nonresponse to hepatitis B vaccines and the kinetics of anti‐HBs production
Author(s) -
Zuckerman Jane N.
Publication year - 1996
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/(sici)1096-9071(199612)50:4<283::aid-jmv1>3.0.co;2-4
Subject(s) - virology , kinetics , hepatitis b virus , production (economics) , hepatitis b , medicine , virus , physics , economics , quantum mechanics , macroeconomics
No empirical data are available for the anti‐HBs titre required for protection against infection with the hepatitis B virus (HBV), but nonresponders to hepatitis B vaccines remain susceptible to infection. There may be an unexplained qualitative difference between hyporesponders and true nonresponders, but there is a clear association with HLA haplotypes. There is no evidence for silent infection with HBV in nonresponders. © 1996 Wiley‐Liss, Inc.