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Hematologic neoplasia and the central nervous system
Author(s) -
Sham Ronald L.,
Phatak Pradyumna D.,
Kouides Peter A.,
Janas Jo Ann S.,
Marder Victor J.
Publication year - 1999
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/(sici)1096-8652(199912)62:4<234::aid-ajh6>3.0.co;2-b
Subject(s) - medicine , multiple myeloma , central nervous system , meningitis , lymphoma , myeloid leukemia , leukemia , complication , hematologic disorders , hematologic disease , acute lymphocytic leukemia , disease , immunology , pathology , lymphoblastic leukemia , pediatrics
Central nervous system (CNS) involvement with malignant cells is a well recognized complication of hematologic neoplasms. A number of disorders such as acute lymphoblastic leukemia and high grade lymphoma frequently involve the CNS and prophylactic therapy is advised. Disorders such as acute myeloid leukemia (AML) and multiple myeloma are less likely to be associated with CNS involvement. This series describes three cases of CNS involvement by malignant hematologic disease: myelomatous meningitis, CNS chloromas complicating AML, and primary lymphomatous meningitis. Am. J. Hematol. 62:234–238, 1999. © 1999 Wiley‐Liss, Inc.