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Effects of hyperthermal stress on the ultrastructure of platelets with reference to the localization of platelet peroxidase and fibrinogen in vivo
Author(s) -
Kurabayashi Hitoshi,
Kubota Kazuo,
Take Hitoshi,
Tamura Kousei,
Shirakura Takuo
Publication year - 1997
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/(sici)1096-8652(199712)56:4<244::aid-ajh8>3.0.co;2-x
Subject(s) - platelet , fibrinogen , peroxidase , chemistry , in vivo , vacuole , ultrastructure , medicine , endocrinology , biochemistry , biology , pathology , enzyme , microbiology and biotechnology , cytoplasm
Ultrastructure of platelets with the localization of platelet peroxidase and fibrinogen through 3‐min 47°C hot‐spring bathing was investigated in eight healthy volunteers. The mean sublingual temperature rose about 1.8°C 5 min after the start of bathing. The frequencies of fold, pseudopods, vacuoles, and centralization were increased after bathing. Platelet peroxidase activity was decreased after bathing. Furthermore, fibrinogen was decreased in α‐granules after bathing. Thus, hyperthermal stress in vivo may activate platelets, resulting in consumption of platelet peroxidase and fibrinogen. Am. J. Hematol. 56:244–247, 1997. © 1997 Wiley‐Liss, Inc.