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Cerebral infarct associated with factor V Leiden mutation in a boy with hemophilia A
Author(s) -
Olcay Lale,
Gürgey Aytemiz,
Topaloğlu Haluk,
Altay Sedat,
Parlak Hülya,
Firat Murat
Publication year - 1997
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/(sici)1096-8652(199711)56:3<189::aid-ajh11>3.0.co;2-6
Subject(s) - factor v leiden , medicine , antithrombin , thrombosis , coagulopathy , factor v , gastroenterology , fibrinogen , thrombophilia , loss of heterozygosity , mutation , pathology , venous thrombosis , allele , heparin , genetics , biology , gene
An 11‐year‐old boy with mild hemophilia A was admitted to our hospital because of focal convulsions. Magnetic resonance imaging showed an old occipital infarct. Protein C, S, antithrombin III, anticardiolipin antibodies and fibrinogen were normal. Heterozygosity for factor V Leiden mutation was detected. We suggest that factor V Leiden mutation should be studied in hemophiliacs with thrombosis. Am. J. Hematol. 56:189–190, 1997. © 1997 Wiley‐Liss, Inc.