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BCL‐2 oncoprotein (p26) in splenic lymphoma with villous lymphocytes: A comparative study with other chronic B‐cell disorders
Author(s) -
Lima Margarida,
Teixeira Maria dos Anjos,
Queirós Maria Luís,
Ribeiro dos Santos Ana Helena,
Justiça Benvindo
Publication year - 1997
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/(sici)1096-8652(199710)56:2<122::aid-ajh9>3.0.co;2-0
Subject(s) - b cell , lymphoma , lymphoproliferative disorders , b cell lymphoma , medicine , pathology , immunology , antibody
We compared the expression of the BCL‐2 oncoprotein (p26) on B cells from 24 patients with splenic lymphoma with circulating villous lymphocytes (SLVL) with that observed on normal, mature B lymphocytes and on neoplastic B cells from 91 patients with other chronic B‐cell malignancies. SLVL B cells showed levels of p26 intermediate between those found on normal B lymphocytes and on neoplastic B cells from patients with other chronic B‐cell lymphoproliferative disorders. Am. J. Hematol. 56:122–125, 1997. © 1997 Wiley‐Liss, Inc.