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Previously undescribed form of B‐cell chronic lymphoid leukemia with IgA expression/secretion and lytic bone lesions
Author(s) -
Dunphy Cherie H.,
Oza Yagnesh V.,
Skelly Milton E.
Publication year - 1997
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/(sici)1096-8652(199707)55:4<208::aid-ajh8>3.0.co;2-w
Subject(s) - immunophenotyping , lytic cycle , bone marrow , pathology , medicine , chronic lymphocytic leukemia , secretion , b cell , leukemia , immunology , cancer research , flow cytometry , antibody , virus
A B‐cell chronic lymphoid leukemia (B‐CLL) associated with IgA expression and secretion is uncommon and has never been described in association with osteolytic bone lesions. We report such a case, defined by cytomorphology and flow cytometric immunophenotyping (FCI). Additional cases may be recognized with the aid of FCI, in order to define the natural history of and best form of therapy for this rare disorder. Am. J. Hematol. 55:208–211, 1997. © 1997 Wiley‐Liss, Inc.