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Low molecular weight heparin stimulates megakaryocytopoiesis in bone‐marrow transplantation patients
Author(s) -
Or Reuven,
Elad Sharon,
Shpilberg Ofer,
Eldor Amiram
Publication year - 1996
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/(sici)1096-8652(199609)53:1<46::aid-ajh11>3.0.co;2-1
Subject(s) - megakaryocytopoiesis , medicine , low molecular weight heparin , heparin , platelet , bone marrow transplantation , bone marrow , transplantation , surgery , hepatic veno occlusive disease , haematopoiesis , gastroenterology , hematopoietic stem cell transplantation , stem cell , megakaryocyte , biology , genetics
The use of low molecular weight heparin (LMWH) as prophylaxis for veno‐occlusive disease of the liver has been studied in patients undergoing bone marrow transplantation (BMT). The present study analyzes the effect of LMWH on the time course of platelet recovery after BMT. Significantly accelerated platelet recovery in conjunction with lessened requirements of platelet transfusions was observed in the LMWH‐treated patients. © 1996 Wiley‐Liss, Inc.