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Absence of CD69 expression on peripheral eosinophils in episodic angioedema and eosinophilia
Author(s) -
Kawano Mitsuhiro,
Muramoto Hiroaki,
Tsunoda Shinichiro,
Koni Ichiro,
Mabuchi Hiroshi,
Yachie Akihiro,
Miyawaki Toshio
Publication year - 1996
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/(sici)1096-8652(199609)53:1<43::aid-ajh10>3.0.co;2-4
Subject(s) - eosinophilia , angioedema , eosinophil , hypereosinophilic syndrome , immunology , cd69 , medicine , peripheral , major basic protein , pathology , t cell , immune system , il 2 receptor , asthma
A 45‐year‐old woman with episodic angioedema and eosinophilia is presented. CD69, which is one of the surface antigens of activated eosinophils, was not expressed on the peripheral eosinophils in this patient, in contrast to hypereosinophilic syndrome. This suggests that CD69, which is not dependent on eosinophil density, may be another useful activation marker of eosinophils to distinguish episodic angioedema and eosinophilia from hypereosinophilic syndrome. © 1996 Wiley‐Liss, Inc.