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An indolent type of Epstein‐Barr virus‐associated T‐cell‐rich B‐cell lymphoma of the skin: Report of a case
Author(s) -
Take Hitoshi,
Kubota Kazuo,
Fukuda Toshio,
Shiome Shogo,
Ishikawa Osamu,
Shirakura Takuo
Publication year - 1996
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/(sici)1096-8652(199607)52:3<221::aid-ajh16>3.0.co;2-i
Subject(s) - hepatosplenomegaly , erythroderma , lymphoma , epstein–barr virus , pathology , virus , polyclonal antibodies , monoclonal , generalized lymphadenopathy , medicine , antibody , b cell , virology , biology , monoclonal antibody , immunology , disease
A 74‐year‐old Japanese man presented with systemic lymphadenopathy, hepatosplenomegaly, and erythroderma in December 1991. A characteristic pattern of anti‐EBV antibodies was suggestive of latent EBV infection. A skin tumor biopsied in April 1993 contained biclonal EBV genomes diffusely in the infiltrate of polyclonal T cells and monoclonal B cells. The clinical course was rather mild in contrast to that of classical EBV‐associated disorders. Our case was considered a rare indolent type of EBV‐associated T‐cell‐rich B‐cell lymphoma of the skin. © 1996 Wiley‐Liss, Inc.