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Central nervous system granulocytic sarcoma in a patient with essential thrombocythemia
Author(s) -
Grande Mario
Publication year - 1996
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/(sici)1096-8652(199601)51:1<64::aid-ajh10>3.0.co;2-b
Subject(s) - essential thrombocythemia , central nervous system , medicine , pathology , myeloid leukemia , sarcoma , leukemia , platelet , cancer research
We report a rare case of central nervous system granulocytic sarcoma (GS) in a patient with essential thrombocythemia (ET). The diagnosis of GS was established by morphological and cytochemical findings (peroxidase and naphthol‐AS‐D‐chloroacetate esterase positivity) of neoplastic cells. GS was detected as an intracranial frontal mass 7 months before the transformation of ET in acute myeloid leukemia and relapsed as two extradural spinal masses during the course of leukemic evolution. © 1996 Wiley‐Liss, Inc.