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Internalization and Cellular Fate of Protein Corona‐Coated Nanoparticles by Multimodal Multi‐Scale Microscopy (Small 22/2025)
Author(s) -
Galdino Flávia E.,
Rabelo Renata S.,
Scarpa Isabella,
Yoneda Juliana S.,
Consonni Sílvio R.,
Paes Leme Adriana F.,
Smith Andrew M.,
Harkiolaki Maria,
Cardoso Mateus B.
Publication year - 2025
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202570174
Nanoparticles In article number 2409065, Mateus B. Cardoso and co‐workers explore the intracellular fate of silica nanoparticles using multimodal microscopy. Cryogenic X‐ray nanotomography and correlative fluorescence imaging reveal detailed nanoparticle trajectories from internalization to perinuclear localization, highlighting vesicle migration and fusion. These findings deepen our understanding of nanoparticle‐cell interactions, supporting advancements in nanomedicine and drug delivery applications.

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