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Polymeric Anti‐Antibiotic Microparticles to Prevent Antibiotic Resistance Evolution (Small 21/2025)
Author(s) -
Koshani Roya,
Yeh ShangLin,
He Zeming,
Narasimhalu Naveen,
vom Steeg Landon G.,
Sim Derek G.,
Woods Robert J.,
Read Andrew F.,
Sheikhi Amir
Publication year - 2025
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202570165
Antibiotic Resistance In article number 2407549, Amir Sheikhi and co‐workers report sevelamer (SEV), a Food and Drug Administration (FDA)‐approved polymeric microparticle, as an adjuvant therapy to combat antimicrobial resistance. SEV captures off‐target vancomycin and daptomycin in the gastrointestinal tract, preventing resistance enrichment in Enterococcus faecium . SEV therapy protects the last‐resort antibiotics, which may address the global antimicrobial resistance crisis. Image created with BioRender.