Photochemical Direct Mono/Di/Trifluoro‐Functionalization of Quinoxalin‐2(1 H )‐ones

Abstract Given the significant applications of quinoxalinones in medicinal, pharmaceutical, and organic chemistry, developing an efficient synthetic approach for their facile assembly has received substantial attention in synthetic chemistry. Conversely, it has been established that incorporating fluorine into organic molecules either alters or enhances the physical, chemical, and biological properties of the target molecules. In this context, the synergic combination of the synthetic and medicinal properties associated with quinoxaline‐2(1 H )‐ones, and the wide chemical landscape associated with fluorine‐containing organic compounds, installing fluorine atom either as a single atom or as di/tri‐substituted groups on the C‐3 position of quinoxalin‐2(1 H )‐one under visible light irradiation is of increasing academic and scientific interests. In this mini‐review article, we covered the recent progress achieved in various visible light‐induced direct functionalization of quinoxaline‐2(1 H )‐ones for accessing diverse C3‐substituted quinoxalinones embedded with mono/di/tri‐substituted fluorine. Despite discussing the advantages, shortcomings, and challenges associated with the reaction discovery, their mechanistic rationalizations are also underscored.