Photoredox‐Catalyzed α‐Arylation of Bromotrifluoroacetone with Electron‐Rich (Hetero)Arenes

Abstract Photoredox‐catalyzed radical addition of bromotrifluoroacetone and (hetero)arenes to carbonyl compounds has been established under mild conditions. The proposed method enables the synthesis of valuable α‐aryl trifluoromethyl ketone compounds, including biologically relevant arene derivatives, with good yields and regioselectivities. This method eliminates competitive bromination using Zn(OAc) 2 as an additive.