Recent Progress in Asymmetric Michael Additions Catalyzed by Chiral Phosphoric Acids

Abstract Chiral phosphoric acids (CPAs) exhibit bifunctional catalytic properties due to their unique structural features and chemical characteristics, leading to their widespread application in various common reactions. In addition, the Michael addition reaction holds significant importance in the field of organic chemistry, particularly among numerous reactions involving carbon–carbon and carbon–heteroatom bond forming. This minireview systematically introduced the structure and catalytic mechanism of chiral phosphoric acid and gave an overview on the development status of Michael addition catalyzed by chiral phosphoric acids, including actual Michael addition and hetero‐Michael addition (aza‐Michael addition, oxo‐Michael addition, phospha‐Michael addition, sulfa‐Michael addition).