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Acid‐Promoted Structural Reorganization of Pull–Pull Alkylidenecyclobutanes: A Cascade Synthesis of Three‐Substituted γ‐Butyrolactones
Author(s) -
Uras Mauro,
Barranco Stefano,
Zedda Fabio,
Frongia Angelo
Publication year - 2025
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202500171
Subject(s) - chemistry , cascade , stereochemistry , combinatorial chemistry , chromatography
An unprecedented acid‐promoted structural reorganization of pull–pull alkylidenecyclobutanes into three‐substituted γ‐butyrolactones, in moderate‐to‐high yields, via a ring closure‐ring contraction followed by intramolecular ring‐opening cyclization is described.
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