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A Case Series and Literature Review of Angiosarcoma With Malignant Effusion—A Challenging Cytologic Diagnosis With Dire Prognostic Implications
Author(s) -
Lam Jamie C. Y.,
Liu Iris Y. H.,
Ng Joanna K. M.,
Li Joshua J. X.
Publication year - 2025
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.25471
Subject(s) - medicine , angiosarcoma , cytology , effusion , series (stratigraphy) , pathology , radiology , surgery , paleontology , biology
ABSTRACT Angiosarcoma with malignant effusion is an uncommon yet clinically aggressive presentation, which poses as a diagnostic pitfall with its overlapping cytomorphologic features with metastatic adenocarcinoma. In this article, two cases reported in the literature were reviewed for cytology, immunocytochemistry, and clinical course. Key clinical hints, useful cytological features, and immunocytochemical markers in the diagnostic approach of this entity are presented.