Front Cover: Fused Nitrogen Bridgehead N , O ‐Acetals as Versatile Scaffolds: Synthetic Strategies, Mechanism and Applications

Fused nitrogen‐bridgehead N , O ‐acetals are found as crucial scaffolds in natural products and biologically active compounds, exhibiting notable pharmaceutical potential. The Review by I. N. Lykakis and co‐workers (DOI: 10.1002/chem.202500413 ) explores their synthetic methodologies, underlying mechanisms, and diverse applications, with a focus on the enantioselective synthesis of complex structures, especially hydropyrrolo‐oxazole and oxazine derivatives, underscoring their significance in organic synthesis.