Front Cover: Organo‐, Metal‐, and Enzyme‐Mediated Stereoselective Transformations of α‐Angelica Lactone (ChemCatChem 10/2025)

The Front Cover illustrates the transformation of α‐angelica lactone into high‐value molecules through three types of catalysis. α‐Angelica lactone is an economical and versatile five‐membered heterocycle obtainable from lignocellulosic biomass. Its name derives from its natural occurrence in the roots of Angelica archangelica , an aromatic medicinal plant historically used in traditional remedies, which also has a long‐standing tradition in European cuisine. Its stems and roots are aromatic, with a flavor reminiscent of licorice, anise, and wild fennel. Starting from this same key ingredient, lactone‐organocatalytic, metal‐catalyzed, and biocatalytic asymmetric processes enable the synthesis of new chiral enantioenriched butenolide‐containing heterocycles. More information can be found in the Review by A. Moutayakine, S. Meninno, and A. Lattanzi (DOI: 10.1002/cctc.202500060). The cover was designed by Luca Meninno.