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Base‐Catalyzed Remote Hydrogermylation of Olefins
Author(s) -
Ahrweiler Eric,
Selmani Aymane,
Schoenebeck Franziska
Publication year - 2025
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.202503573
Subject(s) - catalysis , base (topology) , surface modification , carbon fibers , carbon chain , base metal , work (physics) , computer science , nanotechnology , combinatorial chemistry , materials science , chemistry , chemical engineering , organic chemistry , engineering , mathematics , metallurgy , mathematical analysis , mechanical engineering , algorithm , welding , composite number
Abstract Although remote functionalization has emerged as a powerful strategy for modifying unactivated sites that are traditionally challenging to functionalize, there has been no remote hydrogermylation known to date. This work reports the first remote hydrogermylation of alkenes, achieved through a rare base‐catalyzed approach‐completely free of added transition metal catalysts. The methodology is operationally simple, versatile, and capable of achieving up to 8‐carbon chain walks, overcoming the previous two‐carbon limit of base‐mediated processes.