Transcriptome Landscape of Cancer‐Associated Fibroblasts in Human PDAC (Adv. Sci. 20/2025) | Zendy

Tao Mengyu | Zendy; Liu Wenting | Zendy; Chen Jianhua | Zendy; Liu Rujiao | Zendy; Zou Jianling | Zendy; Yu Bo | Zendy; Wang Chenchen | Zendy; Huang Mingzhu | Zendy; Chen Qingjian | Zendy; Zhang Zhe | Zendy; Chen Zhiyu | Zendy; Sun Haoyu | Zendy; Zhou Cheng | Zendy; Tan Shuguang | Zendy; Zheng Yuxuan | Zendy; Wang Hongxia | Zendy

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Transcriptome Landscape of Cancer‐Associated Fibroblasts in Human PDAC (Adv. Sci. 20/2025)

Author(s) -

Tao Mengyu,

Liu Wenting,

Chen Jianhua,

Liu Rujiao,

Zou Jianling,

Yu Bo,

Wang Chenchen,

Huang Mingzhu,

Chen Qingjian,

Zhang Zhe,

Chen Zhiyu,

Sun Haoyu,

Zhou Cheng,

Tan Shuguang,

Zheng Yuxuan,

Wang Hongxia

Publication year - 2025

Publication title -

advanced science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.388

H-Index - 100

ISSN - 2198-3844

DOI - 10.1002/advs.202570155

Cancer Associated Fibroblasts in Human PDAC During pancreatic ductal adenocarcinoma (PDAC) progression, cancer‐associated fibroblasts (CAFs) undergo dynamic changes, much like vines clinging to trees. The thorny vines represent CDCP1+FTL+ CAFs, which exhibit resistance to ferroptosis inducers (symbolized by the woodpecker). Simultaneously, CAFs secrete various chemokines, akin to blossoms on vines attracting butterflies, thereby promoting the infiltration of myeloid cells. More details can be found in article number 2415196 by Cheng Zhou, Shuguang Tan, Yuxuan Zheng, Hongxia Wang, and co‐workers.

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