Deciphering the Transcription Factor Landscape in Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation (Adv. Sci. 20/2025) | Zendy

Wang Yu | Zendy; Xue Hui | Zendy; Zhu Xiaohui | Zendy; Lin Dong | Zendy; Chen Zheng | Zendy; Dong Xin | Zendy; Chen Junru | Zendy; Shi Mingchen | Zendy; Ni Yuchao | Zendy; Cao Jonathan | Zendy; Wu Rebecca | Zendy; Kang Connie | Zendy; Pang Xinyao | Zendy; Crea Francesco | Zendy; Lin YenYi | Zendy; Collins Colin C. | Zendy; Gleave Martin E. | Zendy; Parolia Abhijit | Zendy; Chinnaiyan Arul | Zendy; Ong Christopher J. | Zendy; Wang Yuzhuo | Zendy

Open Access

Deciphering the Transcription Factor Landscape in Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation (Adv. Sci. 20/2025)

Author(s) -

Wang Yu,

Xue Hui,

Zhu Xiaohui,

Lin Dong,

Chen Zheng,

Dong Xin,

Chen Junru,

Shi Mingchen,

Ni Yuchao,

Cao Jonathan,

Wu Rebecca,

Kang Connie,

Pang Xinyao,

Crea Francesco,

Lin YenYi,

Collins Colin C.,

Gleave Martin E.,

Parolia Abhijit,

Chinnaiyan Arul,

Ong Christopher J.,

Wang Yuzhuo

Publication year - 2025

Publication title -

advanced science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.388

H-Index - 100

ISSN - 2198-3844

DOI - 10.1002/advs.202570153

Neuroendocrine Transdifferentiation Inspired by the silk‐to‐wing narrative, this frontispiece illustrates prostate cancer lineage transition. Adenocarcinoma appears as a caterpillar, entering a dormant chrysalis for reprogramming before emerging as a neuroendocrine prostate cancer butterfly. A drifting DNA helix, interwoven with transcription factor stones in a fluid backdrop, symbolizes the dynamic regulatory shifts driving transdifferentiation. More details can be found in article number 2404938 by Yuzhuo Wang and co‐workers.

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