Open AccessDNA Origami‐Cyanine Nanocomplex for Precision Imaging of KRAS‐Mutant Pancreatic Cancer Cells (Adv. Sci. 19/2025)
Author(s) -
Moon Hyeran,
Du Yancheng,
Choi Sae Rome,
Seo Seongmin,
Cheng Cih,
Elzey Bennett D.,
Choi Jong Hyun,
Han Bumsoo
Publication year - 2025
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.202570144
DNA Origami‐Cyanine Nanocomplex The internalization of DNA origami‐cyanine nanocomplex via micropinocytosis, characterized by membrane ruffling and vesicle formation, is significantly enhanced in pancreatic cancer cells with KRAS mutation. In article number 2410278 by Jong Hyun Choi, Bumsoo Han, and co‐workers, a new molecular imaging method is proposed based on this finding to selectively visualize pancreatic cancer cells in desmoplastic tumors.