Programmable 2D Metal‐Organic Framework Nanosheets for Enzyme‐Like Hydrolysis of Large Proteins (Adv. Funct. Mater. 22/2025)

Metal‐Organic Framework Nanosheets In article number 2504117, Jonathan A. Foster, Tatjana N. Parac‐Vogt, and co‐workers develop metal–organic framework nanosheets with large surface areas as a new class of heterogeneous nanozymes for peptide bond hydrolysis, providing superior active site accessibility and enhanced catalytic reactivity toward a wide range of peptides and proteins.