Targeted Intraoperative Molecular Imaging for Localizing Nonpalpable Tumors and Quantifying Resection Margin Distances | Zendy

Gregory T. Kennedy | Zendy; Feredun Azari | Zendy; Elizabeth Bernstein | Zendy; Isvita Marfatia | Zendy; Azra Din | Zendy; John C. Kucharczuk | Zendy; Philip S. Low | Zendy; Sunil Singhal | Zendy

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Targeted Intraoperative Molecular Imaging for Localizing Nonpalpable Tumors and Quantifying Resection Margin Distances

Author(s) -

Gregory T. Kennedy,

Feredun Azari,

Elizabeth Bernstein,

Isvita Marfatia,

Azra Din,

John C. Kucharczuk,

Philip S. Low,

Sunil Singhal

Publication year - 2021

Publication title -

jama surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.757

H-Index - 176

eISSN - 2168-6262

pISSN - 2168-6254

DOI - 10.1001/jamasurg.2021.3757

Subject(s) - medicine , interquartile range , radiology , surgical margin , lesion , palpation , asymptomatic , pathology , surgery , resection

Complete (R0) resection is the dominant prognostic factor for survival across solid tumor types. Achieving adequate tumor clearance with appropriate margins is particularly difficult in nonpalpable tumors or in situ disease. Previous methods to address this problem have proven time consumptive, impractical, or ineffective.

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