Association of CYP2C19 and CYP2D6 Poor and Intermediate Metabolizer Status With Antidepressant and Antipsychotic Exposure
Author(s) -
F. Milosavljević,
N. Bukvić,
Zorana Pavlović,
Čedo Miljević,
Vesna Pešić,
Espen Molden,
Magnus IngelmanSundberg,
Stefan Leucht,
Marin M. Jukić
Publication year - 2020
Publication title -
jama psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.531
H-Index - 365
eISSN - 2168-6238
pISSN - 2168-622X
DOI - 10.1001/jamapsychiatry.2020.3643
Subject(s) - cyp2d6 , cyp2c19 , medicine , therapeutic drug monitoring , observational study , antipsychotic , pharmacogenetics , pharmacology , pharmacokinetics , psychiatry , genotype , schizophrenia (object oriented programming) , biology , genetics , cytochrome p450 , metabolism , gene
Precise estimation of the drug metabolism capacity for individual patients is crucial for adequate dose personalization.
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