Association of Prenatal Acetaminophen Exposure Measured in Meconium With Risk of Attention-Deficit/Hyperactivity Disorder Mediated by Frontoparietal Network Brain Connectivity | Zendy

Brennan H. Baker | Zendy; Claudia LugoCandelas | Zendy; Haotian Wu | Zendy; Hannah E. Laue | Zendy; Amélie Boivin | Zendy; Virginie Gillet | Zendy; Natalie Aw | Zendy; Tonima Rahman | Zendy; JeanFrançois Lepage | Zendy; Kevin Whittingstall | Zendy; JeanPhilippe Bellenger | Zendy; Jonathan Posner | Zendy; Larissa Takser | Zendy; Andrea Baccarelli | Zendy

Open Access

Association of Prenatal Acetaminophen Exposure Measured in Meconium With Risk of Attention-Deficit/Hyperactivity Disorder Mediated by Frontoparietal Network Brain Connectivity

Author(s) -

Brennan H. Baker,

Claudia LugoCandelas,

Haotian Wu,

Hannah E. Laue,

Amélie Boivin,

Virginie Gillet,

Natalie Aw,

Tonima Rahman,

JeanFrançois Lepage,

Kevin Whittingstall,

JeanPhilippe Bellenger,

Jonathan Posner,

Larissa Takser,

Andrea Baccarelli

Publication year - 2020

Publication title -

jama pediatrics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.004

H-Index - 183

eISSN - 2168-6211

pISSN - 2168-6203

DOI - 10.1001/jamapediatrics.2020.3080

Subject(s) - medicine , attention deficit hyperactivity disorder , meconium , pregnancy , pediatrics , offspring , cohort study , acetaminophen , psychiatry , anesthesia , fetus , biology , genetics

Despite evidence of an association between prenatal acetaminophen exposure and attention-deficit/hyperactivity disorder (ADHD) in offspring, the drug is not contraindicated during pregnancy, possibly because prior studies have relied on maternal self-report, failed to quantify acetaminophen dose, and lacked mechanistic insight.

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