Association of Patent Ductus Arteriosus Ligation With Death or Neurodevelopmental Impairment Among Extremely Preterm Infants | Zendy

Dany E. Weisz | Zendy; Lucia Mirea | Zendy; Erin Rosenberg | Zendy; Maximus Jang | Zendy; Linh Ly | Zendy; Paige Church | Zendy; Edmond Kelly | Zendy; S. Joseph Kim | Zendy; Amish Jain | Zendy; Patrick J. McNamara | Zendy; Prakesh S. Shah | Zendy

Open Access

Association of Patent Ductus Arteriosus Ligation With Death or Neurodevelopmental Impairment Among Extremely Preterm Infants

Author(s) -

Dany E. Weisz,

Lucia Mirea,

Erin Rosenberg,

Maximus Jang,

Linh Ly,

Paige Church,

Edmond Kelly,

S. Joseph Kim,

Amish Jain,

Patrick J. McNamara,

Prakesh S. Shah

Publication year - 2017

Publication title -

jama pediatrics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.004

H-Index - 183

eISSN - 2168-6211

pISSN - 2168-6203

DOI - 10.1001/jamapediatrics.2016.5143

Subject(s) - medicine , ductus arteriosus , ligation , pediatrics

Observational studies have associated patent ductus arteriosus (PDA) ligation among preterm infants with adverse neonatal outcomes and neurodevelopmental impairment in early childhood, with a resultant secular trend away from surgical treatment. However, to our knowledge, studies have inadequately addressed sources of residual bias, including survival bias and major neonatal morbidities arising before exposure to ligation.

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