Cost-effectiveness and Budgetary Consequence Analysis of Durvalumab Consolidation Therapy vs No Consolidation Therapy After Chemoradiotherapy in Stage III Non–Small Cell Lung Cancer in the Context of the US Health Care System
Author(s) -
Steven D. Criss,
Meghan J. Mooradian,
Deirdre F. Sheehan,
Leyre Zubiri,
Melissa Lumish,
Justin F. Gainor,
Kerry L. Reynolds,
Chung Yin Kong
Publication year - 2018
Publication title -
jama oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.846
H-Index - 99
eISSN - 2374-2445
pISSN - 2374-2437
DOI - 10.1001/jamaoncol.2018.5449
Subject(s) - medicine , durvalumab , chemoradiotherapy , lung cancer , context (archaeology) , oncology , cancer , immunotherapy , pembrolizumab , paleontology , biology
In early 2018, durvalumab became the first immunotherapy to be approved for adjuvant treatment of patients with unresectable stage III non-small cell lung cancer (NSCLC) whose cancer has not progressed after definitive chemoradiotherapy. However, the cost-effectiveness and potential economic implications of using this high-priced therapy in this indication are unknown to date.
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