Individualized Adaptive Stereotactic Body Radiotherapy for Liver Tumors in Patients at High Risk for Liver Damage | Zendy

Mary Feng | Zendy; Krithika Suresh | Zendy; Matthew J. Schipper | Zendy; Latifa Bazzi | Zendy; Edgar BenJosef | Zendy; M.M. Matuszak | Zendy; Neehar D. Parikh | Zendy; Theodore H. Welling | Zendy; Daniel P. Normolle | Zendy; Randall K. Ten Haken | Zendy; Theodore S. Lawrence | Zendy

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Individualized Adaptive Stereotactic Body Radiotherapy for Liver Tumors in Patients at High Risk for Liver Damage

Author(s) -

Mary Feng,

Krithika Suresh,

Matthew J. Schipper,

Latifa Bazzi,

Edgar BenJosef,

M.M. Matuszak,

Neehar D. Parikh,

Theodore H. Welling,

Daniel P. Normolle,

Randall K. Ten Haken,

Theodore S. Lawrence

Publication year - 2017

Publication title -

jama oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 8.846

H-Index - 99

eISSN - 2374-2445

pISSN - 2374-2437

DOI - 10.1001/jamaoncol.2017.2303

Subject(s) - medicine , indocyanine green , liver function , hepatocellular carcinoma , cirrhosis , liver function tests , gastroenterology , oncology , surgery

Patients with preexisting liver dysfunction could benefit the most from personalized therapy for liver tumors to balance maximal tumor control and minimal risk of liver failure. We designed an individualized adaptive trial testing the hypothesis that adapting treatment based on change in liver function could optimize the therapeutic index for each patient.

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