Association Between Genomic Metrics and Immune Infiltration in Triple-Negative Breast Cancer | Zendy

Thomas Karn | Zendy; Tingting Jiang | Zendy; Christos Hatzis | Zendy; Nicole Sänger | Zendy; Ahmed ElBalat | Zendy; Achim Rody | Zendy; Uwe Holtrich | Zendy; Sven Becker | Zendy; Giampaolo Bianchini | Zendy; Lajos Pusztai | Zendy

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Association Between Genomic Metrics and Immune Infiltration in Triple-Negative Breast Cancer

Author(s) -

Thomas Karn,

Tingting Jiang,

Christos Hatzis,

Nicole Sänger,

Ahmed ElBalat,

Achim Rody,

Uwe Holtrich,

Sven Becker,

Giampaolo Bianchini,

Lajos Pusztai

Publication year - 2017

Publication title -

jama oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 8.846

H-Index - 99

eISSN - 2374-2445

pISSN - 2374-2437

DOI - 10.1001/jamaoncol.2017.2140

Subject(s) - immune system , breast cancer , medicine , triple negative breast cancer , immunotherapy , oncology , tumor infiltrating lymphocytes , cancer research , immunology , cancer

Why some triple-negative breast cancers (TNBCs) have high and others have low immune cell infiltration is unknown. Understanding how immune surveillance shapes the cancer genome could help in the selection of patients and the development of more effective immunotherapy strategies.

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