Comparison of Plasma Phosphorylated Tau Species With Amyloid and Tau Positron Emission Tomography, Neurodegeneration, Vascular Pathology, and Cognitive Outcomes | Zendy

Michelle M. Mielke | Zendy; Ryan D. Frank | Zendy; Jeffrey L. Dage | Zendy; Andreas Jeromin | Zendy; Nicholas J. Ashton | Zendy; Kaj Blennow | Zendy; Thomas K. Karikari | Zendy; Eugeen Vanmechelen | Zendy; Henrik Zetterberg | Zendy; Alicia AlgecirasSchimnich | Zendy; David S. Knopman | Zendy; Val J. Lowe | Zendy; Guojun Bu | Zendy; Prashanthi Vemuri | Zendy; Jonathan GraffRadford | Zendy; Clifford R. Jack | Zendy; Ronald C. Petersen | Zendy

Open Access

Comparison of Plasma Phosphorylated Tau Species With Amyloid and Tau Positron Emission Tomography, Neurodegeneration, Vascular Pathology, and Cognitive Outcomes

Author(s) -

Michelle M. Mielke,

Ryan D. Frank,

Jeffrey L. Dage,

Andreas Jeromin,

Nicholas J. Ashton,

Kaj Blennow,

Thomas K. Karikari,

Eugeen Vanmechelen,

Henrik Zetterberg,

Alicia AlgecirasSchimnich,

David S. Knopman,

Val J. Lowe,

Guojun Bu,

Prashanthi Vemuri,

Jonathan GraffRadford,

Clifford R. Jack,

Ronald C. Petersen

Publication year - 2021

Publication title -

jama neurology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.298

H-Index - 231

eISSN - 2168-6157

pISSN - 2168-6149

DOI - 10.1001/jamaneurol.2021.2293

Subject(s) - standardized uptake value , interquartile range , positron emission tomography , medicine , fractional anisotropy , white matter , hyperintensity , pathology , magnetic resonance imaging , nuclear medicine , psychology , radiology

Cerebrospinal fluid phosphorylated tau (p-tau) 181, p-tau217, and p-tau231 are associated with neuropathological outcomes, but a comparison of these p-tau isoforms in blood samples is needed.

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