Association of Reperfusion After Thrombolysis With Clinical Outcome Across the 4.5- to 9-Hours and Wake-up Stroke Time Window | Zendy

Bruce Campbell | Zendy; Henry Ma | Zendy; Mark Parsons | Zendy; Leonid Churilov | Zendy; Nawaf Yassi | Zendy; Timothy Kleinig | Zendy; Chung Y. Hsu | Zendy; Helen M. Dewey | Zendy; Kenneth Butcher | Zendy; Bernard Yan | Zendy; Patricia Desmond | Zendy; Tissa Wijeratne | Zendy; Sami Curtze | Zendy; P. Alan Barber | Zendy; Deidre Anne De Silva | Zendy; Vincent Thijs | Zendy; Christopher Levi | Zendy; Christopher F. Bladin | Zendy; Gagan Sharma | Zendy; Andrew Bivard | Zendy; Geoffrey A. Donnan | Zendy; Stephen M. Davis | Zendy

Open Access

Association of Reperfusion After Thrombolysis With Clinical Outcome Across the 4.5- to 9-Hours and Wake-up Stroke Time Window

Author(s) -

Bruce Campbell,

Henry Ma,

Mark Parsons,

Leonid Churilov,

Nawaf Yassi,

Timothy Kleinig,

Chung Y. Hsu,

Helen M. Dewey,

Kenneth Butcher,

Bernard Yan,

Patricia Desmond,

Tissa Wijeratne,

Sami Curtze,

P. Alan Barber,

Deidre Anne De Silva,

Vincent Thijs,

Christopher Levi,

Christopher F. Bladin,

Gagan Sharma,

Andrew Bivard,

Geoffrey A. Donnan,

Stephen M. Davis

Publication year - 2020

Publication title -

jama neurology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.298

H-Index - 231

eISSN - 2168-6157

pISSN - 2168-6149

DOI - 10.1001/jamaneurol.2020.4123

Subject(s) - medicine , thrombolysis , modified rankin scale , stroke (engine) , randomized controlled trial , intracerebral hemorrhage , randomization , cardiology , perfusion scanning , anesthesia , ischemia , perfusion , myocardial infarction , ischemic stroke , subarachnoid hemorrhage , mechanical engineering , engineering

Intravenous alteplase reduces disability after ischemic stroke in patients 4.5 to 9 hours after onset and with wake-up onset stroke selected using perfusion imaging mismatch. However, whether the benefit is consistent across the 4.5- to 6-hours, 6- to 9-hours, and wake-up stroke epochs is uncertain.

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