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Tailoring the Approach to Embolic Stroke of Undetermined Source
Author(s) -
Hooman Kamel,
Alexander E. Merkler,
Costantino Iadecola,
Ajay Gupta,
Babak B. Navi
Publication year - 2019
Publication title -
jama neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.298
H-Index - 231
eISSN - 2168-6157
pISSN - 2168-6149
DOI - 10.1001/jamaneurol.2019.0591
Subject(s) - embolic stroke , medicine , stroke (engine) , subclinical infection , patent foramen ovale , atrial fibrillation , randomized controlled trial , cardiology , foramen ovale (heart) , intensive care medicine , ischemic stroke , ischemia , mechanical engineering , migraine , engineering
One-third of ischemic strokes have no identifiable cause after standard evaluation. In 2014, researchers termed these embolic strokes of undetermined source (ESUS) and argued that this entity would respond to anticoagulation. Two recent randomized clinical trials have not upheld this hypothesis, leading to questions about the ESUS concept.

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