Molecular Characterization of Lipoaspirates Used in Regenerative Head and Neck Surgery | Zendy

Kariem Sharaf | Zendy; A Kleinsasser | Zendy; Sabina SchwenkZieger | Zendy; Olivier Gires | Zendy; Henrik Schinke | Zendy; Vera Kohlbauer | Zendy; Mark Jakob | Zendy; Martin Canis | Zendy; Frank Haubner | Zendy

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Molecular Characterization of Lipoaspirates Used in Regenerative Head and Neck Surgery

Author(s) -

Kariem Sharaf,

A Kleinsasser,

Sabina SchwenkZieger,

Olivier Gires,

Henrik Schinke,

Vera Kohlbauer,

Mark Jakob,

Martin Canis,

Frank Haubner

Publication year - 2019

Publication title -

jama facial plastic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.815

H-Index - 59

eISSN - 2168-6092

pISSN - 2168-6076

DOI - 10.1001/jamafacial.2019.0851

Subject(s) - medicine , wound healing , stromal vascular fraction , adipose tissue , vascular endothelial growth factor , stromal cell , pathology , mesenchymal stem cell , fibrosis , surgery , vegf receptors

Adipose-derived mesenchymal stem cells (ASCs) have been used commonly in regenerative medicine and increasingly for head and neck surgical procedures. Lipoaspiration with centrifugation is purported to be a mild method for the extraction of ASCs used for autologous transplants to restore tissue defects or induce wound healing. The content of ASCs, their paracrine potential, and cellular potential in wound healing have not been explored for this method to our knowledge.

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