Human Induced Pluripotent Stem Cell–Derived Motor Neuron Transplant for Neuromuscular Atrophy in a Mouse Model of Sciatic Nerve Injury | Zendy

JonPaul Pepper | Zendy; Tiffany V. Wang | Zendy; Valerie Hennes | Zendy; Soo Yeon Sun | Zendy; Justin K. Ichida | Zendy

Open Access

Human Induced Pluripotent Stem Cell–Derived Motor Neuron Transplant for Neuromuscular Atrophy in a Mouse Model of Sciatic Nerve Injury

Author(s) -

JonPaul Pepper,

Tiffany V. Wang,

Valerie Hennes,

Soo Yeon Sun,

Justin K. Ichida

Publication year - 2016

Publication title -

jama facial plastic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.815

H-Index - 59

eISSN - 2168-6092

pISSN - 2168-6076

DOI - 10.1001/jamafacial.2016.1544

Subject(s) - medicine , induced pluripotent stem cell , motor neuron , sciatic nerve , atrophy , human induced pluripotent stem cells , neuroscience , stem cell , muscle atrophy , anatomy , neuromuscular junction , pathology , embryonic stem cell , biology , biochemistry , disease , gene , genetics

Human motor neurons may be reliably derived from induced pluripotent stem cells (iPSCs). In vivo transplant studies of human iPSCs and their cellular derivatives are essential to gauging their clinical utility.

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