Neonatal Linear IgA Bullous Dermatosis Mediated by Breast Milk–Borne Maternal IgA
Author(s) -
Shohei Egami,
Chihiro Suzuki,
Yuichi Kurihara,
Jun Yamagami,
Akiharu Kubo,
Takeru Funakoshi,
Wataru Nishie,
Kazuya Matsumura,
Takahiro Matsushima,
Miho Kawaida,
Michiie Sakamoto,
Masayuki Amagai
Publication year - 2021
Publication title -
jama dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.128
H-Index - 166
eISSN - 2168-6084
pISSN - 2168-6068
DOI - 10.1001/jamadermatol.2021.2392
Subject(s) - medicine , asymptomatic , autoantibody , immunoglobulin a , pathology , immunology , breast milk , antibody , immunoglobulin g , biology , biochemistry
Neonatal linear immunoglobulin A (IgA) bullous dermatosis (LABD) is a rare disease that can be fatal when associated with respiratory failure. All previously reported cases of neonatal LABD have been in newborns with healthy asymptomatic mothers, and the pathogenic IgA was of unknown origin.
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